Published Book

(1)Shirato H, Taguchi H:“Radiation Therapy”, Basics and Clinical, Gstroenterology, Nishimurasyoten, Inc., 1341-1344, 2015

International Collaborative Papers

(1) Ohira H, Birnie DH, Pena E, Bernick J, Mc Ardle B, Leung E, Wells GA, Yoshinaga K, Tsujino I, Sato T, Manabe O, Oyama-Manabe N, Nishimura M, Tamaki N, Dick A, Dennie C, Klein R, Renaud J, deKemp RA, Ruddy TD, Chow BJ, Davies R, Hessian R, Liu P, Beanlands RS, Nery PB: “Comparison of (18)f-fluorodeoxyglucose positron emission tomography (fdg pet) and cardiac magnetic resonance (cmr) in corticosteroid-naive patients with conduction system disease due to cardiac sarcoidosis”, E J of Nucl Med Mol Imaging. 2016;43:259-269 (2016) [Overseas journal]

(2) Cui Y, Tha KK, Terasaka S, Yamaguchi S, Wang J, Kudo K, Xing L, Shirato H, Li R: “Prognostic Imaging Biomarkers in Glioblastoma: Development and Independent Validation on the Basis of Multiregion and Quantitative Analysis of MR Images”, Radiology, 278(2):546-53, (2015) [Overseas journal] *i) ii) ○

(3) Le QT, Shirato H, Giaccia AJ, Koong AC: “Emerging Treatment Paradigms in Radiation Oncology”, Clin Cancer Res., 1;21(15):3393-401, (2015) [Overseas journal] *i) ii) ○

Other Original Papers

-major papers only

・Japanese Journals (including those in English)

(1) Mimura R, Kato F, Tha KK, Kudo K, Konno Y, Oyama-Manabe N, Kato T, Watari H, Sakuragi N, Shirato H: “Comparison between borderline ovarian tumors and carcinomas using semi-automated histogram analysis of diffusion-ｗeighted imaging: focusing on solid components”, Jpn J Radiol. 2016 Mar;34(3):229-37. doi: 10.1007/s11604-016-0518-6. Epub 2016 Jan 21. (2016)

(2) Maeda K, Yasui H, Matsuura T, Yamamori T, Suzuki M, Nagane M, Nam JM, Inanami O, Shirato H: “Evaluation of the relative biological effectiveness of spot-scanning proton irradiation in vitro”, J Radiat Res. 2016 Jun;57(3):307-11. doi: 10.1093/jrr/rrv101. (2016) *i)

(3) Maeda K, Yasui H, Matsuura T, Yamamori T, Suzuki M, Nagane M, Nam JM, Inanami O, Shirato H: “Evaluation of the relative biological effectiveness of spot-scanning proton irradiation in vitro”, J. Radiat. Res., 2016 Jun;57(3):307-11. doi: 10.1093/jrr/rrv101. Epub 2016 Feb 1. (2016) *i)

(4) Umegaki K: “Development of an Innovative Proton Beam Therapy System”, Journal of Industry-Academia-Government Collaboration, 1(12), 4-7, (2016)

(5) Shirato H: “Progress of Radiation Therapy System (Feature article, The leading edge in Cancer Radiation Therapy)”, The Journal of the Japan Medical Association, 144:233-236, (2015)

(6) Oyama-Manabe N: “Myocardial perfusion imaging for evaluating viability with contrast enhanced MRI”,Jpn Journal of Diagnostic Imaging (Rinsho-gazou), 31,159-166, (2015)

(7) Oyama-Manabe N: “Left atrial myxoma, Adipoma, Metastatic cardiac tumor, Fibroma, Malignant lymphoma, ‘CT/MRI for cardiovascular disease’”, Jpn Journal of Diagnostic Imaging, 35, 944-953, (2015)

(8) Oyama-Manabe N: “Heart CT/MRI update: Cardiac perfusion CT”, Jpn Journal of Clinical Radiology, 60, 212-222, (2015)

(9) Kudo K: “Basic theory of perfusion imaging”, NICHIDOKU-IHO, 60(2): 6-19, (2015)

(10) Ishikawa M, Nagase N, Matsuura T, Hiratsuka J, Suzuki R, Miyamoto N, Sutherland KL, Fujita K, Shirato H: “Development of a wavelength-separated type scintillator with optical fiber (SOF) dosimeter to compensate for the Cerenkov radiation effect”, J Radiat Res., 56(2):372-81. (2015)

・Overseas Journals

(1) Matsuura T, Fujii Y, Takao S, Yamada T, Matsuzaki Y, Miyamoto N, Takayanagi T, Fujitaka S, Shimizu S, Shirato H: “Development and evaluation of a short-range applicator for treating superficial moving tumors with respiratory-gated spot-scanning proton therapy using real-time image guidance”, Phys Med Biol., 61(4):1515-31 (2016) *i)

(2) Takao S, Miyamoto N, Matsuura T, Onimaru R, Katoh N, Inoue T, Sutherland KL, Suzuki R, Shirato H, Shimizu S: “Intrafractional Baseline Shift or Drift of Lung Tumor Motion During Gated Radiation Therapy With a Real-Time Tumor-Tracking System”, Int J Radiat Oncol Biol Phys, 94(1):172-80 (2016) *i)

(3) Harada K, Katoh N, Suzuki R, Ito YM, Shimizu S, Onimaru R, Inoue T, Miyamoto N, Shirato H. “Evaluation of the motion of lung tumors during stereotactic body radiation therapy (SBRT) with four-dimensional computed tomography (4DCT) using real-time tumor-tracking radiotherapy system (RTRT)”, Phys Med., 32(2):305-11. (2016) *i)

(4) Fujima N, Osanai T, Shimizu Y, Yoshida A, Harada T, Nakayama N, Kudo K, Houkin K, Shirato H: “Utility of noncontrast-enhanced time-resolved four-dimensional MR angiography with a vessel-selective technique for intracranial arteriovenous malformations” , J Magn Reson Imaging, in press (2016) *i)

(5) Fujima N, Yoshida D, Sakashita T, Homma A, Tsukahara A, Tha KK, Kudo K, Shirato H: “Usefulness of Pseudocontinuous Arterial Spin-Labeling for the Assessment of Patients with Head and Neck Squamous Cell Carcinoma by Measuring Tumor Blood Flow in the Pretreatment and Early Treatment Period”, AJNR Am J Neuroradiol., Feb;37(2):342-8, (2016) *i)

(6) Kato F, Kudo K, Yamashita H, Wang J, Hosoda M, Hatanaka KC, Mimura R, Oyama-Manabe N, Shirato H: “Differences in morphological features and minimum apparent diffusion coefficient values among breast cancer subtypes using 3-tesla MRI”, Eur J Radiol., 85(1):96-102. (2016)

(7) Shirato H: “Radiotherapy: characteristics of particle therapy and its perspective”, Annals of Oncology, 2015 Nov EL19;26:65-65 (2015)

(8) Wang J, Kato F, Oyama-Manabe N, Li R, Cui Y, Tha KK, Yamashita H, Kudo K, Shirato H: “Identifying Triple-Negative Breast Cancer Using Background Parenchymal Enhancement Heterogeneity on Dynamic Contrast-Enhanced MRI: A Pilot Radiomics Study”, PLoS One., 10(11):e0143308. (2015) *i)

(9) Sugano Y, Mizuta M, Takao S, Shirato H, Sutherland KL, Date H: “”, Med Phys., 42;11:6203-6210 (2015)

(10) Harada Y, Hirata K, Nakayama N, Yamaguchi S, Yoshida M, Onodera S, Manabe O, Shiga T, Terae S, Shirato H, Tamaki N: “Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation”, Acta Radiol Open., 27;4(6):2058460115584112, (2015)

(11) Fujima N, Kameda H, Tsukahara A, Yoshida D, Sakashita T, Homma A, Tha KK, Kudo K, Shirato H: “Diagnostic value of tumor blood flow and its histogram analysis obtained with pCASL to differentiate sinonasal malignant lymphoma from squamous cell carcinoma”, Eur J Radiol., 84(11):2187-93, (2015) *i)

(12) Onimaru R, Shirato H, Shibata T, Hiraoka M, Ishikura S, Karasawa K, Matsuo Y, Kokubo M, Shioyama Y, Matsushita H, Ito Y, Onishi H: “Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer with PTV<100cc using a continual reassessment method (JCOG0702)”, Radiother Oncol., 116(2):276-80, (2015)

(13) Aoyama H, Tago M, Shirato H: Japanese Radiation Oncology Study Group 99-1 (JROSG 99-1) Investigators: “Stereotactic Radiosurgery With or Without Whole-Brain Radiotherapy for Brain Metastases: Secondary Analysis of the JROSG 99-1 Randomized Clinical Trial”, JAMA Oncol, 1(4):457-64, (2015)

(14) Kunimatsu J, Miyamoto N, Ishikawa M, Shirato H, Tanaka M: “Application of radiosurgical techniques to produce a primate model of brain lesions”, Front Syst Neurosci, 24;9:67. (2015)

(15) Furusawa J, Homma A, Onimaru R, Sakashita T, Yoshida D, Hatakeyama H, Mizumachi T, Kano S, Tsuchiya K, Yasuda K, Shirato H, Fukuda S: “Indications for superselective intra-arterial cisplatin infusion and concomitant radiotherapy in cases of hypopharyngeal cancer”, Auris Nasus Larynx, 42(6):443-8, (2015)

(16) Homma A, Nakamaru Y, Sakashita T, Onimaru R, Terasaka S, Tsuchiya K, Yoshida D, Yasuda K, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Shirato H, Fukuda S: “Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus: A single institution experience”, Auris Nasus Larynx, 42(5):377-81 (2015)

(17) Sakuhara Y, Nishio S, Morita K, Abo D, Hasegawa Y, Yuasa N, Mochizuki T, Soyama T, Oba K, Shirato H, Kudo K: “Transcatheter Arterial Embolization with Ethanol Injection in Symptomatic Patients with Enlarged Polycystic Kidneys”, Radiology, 277(1):277-85, (2015)

(18) Mori T, Onimaru R, Onodera S, Tsuchiya K, Yasuda K, Hatakeyama H, Kobayashi H, Terasaka S, Homma A, Shirato H: “Olfactory neuroblastoma: the long-term outcome and late toxicity of multimodal therapy including radiotherapy based on treatment planning using computed tomography”, Radiat Oncol., 15;10(1):88. (2015)

(19) Sakashita T, Homma A, Hatakeyama H, Furusawa J, Kano S, Mizumachi T, Iizuka S, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S: “Comparison of acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas: A single-institution retrospective study in Japan”, Acta Otolaryngol., 135(8):853-8. (2015)

(20) Sakashita T, Homma A, Hatakeyama H, Furusawa J, Kano S, Mizumachi T, Iizuka S, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S: “Clinical outcomes of weekly cisplatin chemoradiotherapy for patients with pyriform sinus cancer”, Int J Clin Oncol., 20(6):1081-5. (2015)

(21) Fujima N, Kudo K, Tsukahara A, Yoshida D, Sakashita T, Homma A, Tha KK, Shirato H: “Measurement of tumor blood flow in head and neck squamous cell carcinoma by pseudo-continuous arterial spin labeling: comparison with dynamic contrast-enhanced MRI”, J Magn Reson Imaging, 41(4):983-91, (2015)

(22) Homma A, Nakamaru Y, Sakashita T, Onimaru R, Terasaka S, Tsuchiya K, Yoshida D, Yasuda K, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Shirato H, Fukuda S: “Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus: A single institution experience”, Auris Nasus Larynx, 42(5):377-81, (2015)

(23) Ishihara S, Yasuda M, Ishizu A, Ishikawa M, Shirato H, Haga H: “Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells”, Oncotarget, 10;6(7):4602-14 (2015)

(24) Yamaguchi S, Hirata K, Kaneko S, Kobayashi H, Shiga T, Kobayashi K, Onimaru R, Shirato H, Tamaki N, Terasaka S, Houkin K: “Combined use of 18 F-FDG PET and corticosteroid for diagnosis of deep-seated primary central nervous system lymphoma without histopathological confirmation”, Acta Neurochir (Wien), 157(2):187-94 (2015)

(25) Mizumachi T, Homma A, Kakizaki T, Sakashita T, Kano S, Hatakeyama H, Tsuchiya K, Yasuda K, Onimaru R, Shirato H, Taguchi J, Shimizu Y, Kinoshita I, Akita H, Fukuda S: “Feasibility and efficacy of induction docetaxel, cisplatin, and 5-fluorouracil chemotherapy combined with concurrent weekly cisplatin chemoradiotherapy for locally advanced head and neck squamous cell carcinoma”, Int J Clin Oncol., 20(3):431-7 (2015)

(26) Ishizaka K, Kato F, Terae S, Mito S, Oyama-Manabe N, Kamishima T, Nakanishi M, Sugimori H, Hamaguchi H, Shirato H: “Bilateral breast MRI by use of dual-source parallel radiofrequency excitation and image-based shimming at 3 Tesla: improvement in homogeneity on fat-suppression imaging”, Radiol Phys Technol., 8(1):4-12 (2015)

(27) Kato F, Oyama-Manabe N, Sakuhara Y, Mito S, Takahashi M, Sakamoto T, Hosoda M, Terae S, Shirato H: “Earlier and better high-resolution single breast imaging during bilateral breast dynamic scans at 3-T MRI: comparison with post dynamic high-resolution imaging”, Breast Cancer, 22;5:475-479 (2015)

(28) Hirata Y, Miyamoto N, Shimizu M, Yoshida M, Hiramoto K, Ichikawa Y, Kaneko S, Sasagawa T, Hiraoka M, Shirato H: “International standardization of four dimensional radiotherapy system – Enhancement of effects of irradiation and assurance of safety”, Synthesiology-English edition, 7(4): 229-238 (2015) *ii)

(29) Watanabe S, Okamoto S, Shiga T, Inoue T, Hirata K, Magota K, Nishijima K, Kuge Y, Shirato H, Tamaki N: “Respiratory-gated FMISO-PET CT for the quantitative evaluation of hypoxia in non-small cell lung cancer”, J Nucl Med., 127(56):3 (2015)

(30) Watanabe S, Okamoto S, Shiga T, Inoue T, Hirata K, Magota K, Nishijima K, Kuge Y, Shirato H, Tamaki N: “Respiratory-gated FMISO-PET/CT detects tumor hypoxia with higher sensitivity in non-small cell lung cancer”, Eur J Nucl Med Mol Imaging., OP144;42:S61-S61 (2015)

(31) Fujima N, Nakamaru Y, Sakashita T, Homma A, Tsukahara A, Kudo K, Shirato H: “Differentiation of squamous cell carcinoma and inverted papilloma using non-invasive MR perfusion imaging”, Dentomaxillofac Radiol., 44(9):20150074. (2015) *i)

(32) Harada T, Abe T, Kato F, Matsumoto R, Fujita H, Murai S, Miyajima N, Tsuchiya K, Maruyama S, Kudo K, Shinohara N: “Five-point Likert scaling on MRI predicts clinically significant prostate carcinoma”, BMC Urol., 4;15:91, (2015)

(33) Homma A, Sakashita T, Hatakeyama H, Kano S, Mizumachi T, Nakamaru Y, Yoshida D, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S: “The efficacy of superselective intra-arterial infusion with concomitant radiotherapy for adenoid cystic carcinoma of the head and neck”, Acta Otolaryngol., 135(9):950-4, (2015)

(34) Shibasaki S, Takahashi N, Homma S, Nishida M, Shimokuni T, Yoshida T, Kawamura H, Oyama-Manabe N, Kudo K, Taketomi A: “Use of transabdominal ultrasonography to preoperatively determine T-stage of proven colon cancers”, Abdom Imaging., 40(6):1441-50, (2015)

(35) Manabe O, Hattori N, Yamaguchi S, Hirata K, Kobayashi K, Terasaka S, Kobayashi H, Motegi H, Shiga T, Magota K, Oyama-Manabe N, Nishijima K, Kuge Y, Tamaki N: “Oligodendroglial component complicates the prediction of tumour grading with metabolic imaging”, Eur J Nucl Med Mol Imaging., 42, 896-904, (2015)

(36) Mori Y, Manabe O, Naya M, Tomiyama Y, Yoshinaga K, Magota K, Oyama-Manabe N, Hirata K, Tsutsui H, Tamaki N, Katoh C: “Improved spillover correction model to quantify myocardial blood flow by 11C-acetate PET: comparison with 15O-H 2O PET”, Ann Nucl Med., 29(1):15-20, (2015)