{"id":83,"date":"2021-03-17T11:08:37","date_gmt":"2021-03-17T02:08:37","guid":{"rendered":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb2.med\/Root\/?page_id=83"},"modified":"2021-03-17T11:08:37","modified_gmt":"2021-03-17T02:08:37","slug":"publications2019","status":"publish","type":"page","link":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/publications2019.html","title":{"rendered":"\u8457\u66f8\u30fb\u7dcf\u8ad6\u3000April 2019 \u2013 March 2020"},"content":{"rendered":"
\n

International Collaborative Papers<\/h3>\n
    \n
  1. Jihun Kwon, Rajalekha M. Rajamahendiran, Needa A. Virani, Sijumon Kunjachan, Erin Snay, Max Harlacher, Marios Myronakis, Shinichi Shimizu<\/u>, Hiroki Shirato<\/u>, Tomasz J. Czernuszewicz, Ryan Gessner, Ross Berbeco. Use of 3D contrast-enhanced ultrasound to evaluate tumor microvasculature after nanoparticle-mediated modulation. Ultrasound in Medicine & Biology<\/em>, in press [Overseas journal] *, i)<\/li>\n
  2. Yusuke Nomura, Qiong Xu<\/u>, Hao Peng<\/u>, Seishin Takao<\/u>, Shinichi Shimizu<\/u>, Lei Xing<\/u> and Hiroki Shirato<\/u>. Modified fast adaptive scatter kernel superposition (mfASKS) correction and its dosimetric impact on CBCT-based proton therapy dose calculation,in press Med Phys. <\/em>[Overseas journal] *, i), ii) \u25cb<\/li>\n
  3. Yusuke Nomura, Jeff Wang<\/u>, Hiroki Shirato<\/u>, Shinichi Shimizu<\/u> and Lei Xing<\/u>. Fast spot-scanning proton dose calculation method using a three-dimensional convolutional neural network. In press, Physics in Medicine and Biology<\/em>. [Overseas journal] *, i), ii) \u25cb<\/li>\n
  4. Kato F, Kudo K<\/u>, Yamashita H, Baba M, Shimizu A, Oyama-Manabe N<\/u>, Kinoshita R, Li R<\/u>, Shirato H<\/u> Predicting Metastasis in Clinically Negative Axillary Lymph Nodes with Minimum Apparent Diffusion Coefficient Value in Luminal A-like Breast Cancer. Breast Cancer<\/em>. 2019 Sep;26(5):628-636. [Overseas journal] *, i), ii), \u25cb<\/li>\n
  5. Takayanagi, Taisuke & Uesaka, Tomoki & Kitaoka, Masanori & Unlu, Mehmet<\/u> & Umegaki, Kikuo<\/u> & Shirato, Hiroki<\/u> & Xing, Lei<\/u> & Matsuura, Taeko<\/u>. A novel range-verification method using ionoacoustic wave generated from spherical gold markers for particle-beam therapy: a simulation study (2019) Scientific Reports<\/em>. 2019 Mar 8;9(1):4011. doi:. 10.1038\/s41598-019-38889-w. [Overseas journal] *, i), ii), \u25cb<\/li>\n
  6. Wu PH<\/u>, Onodera Y<\/u>, Recuenco FC<\/u>, Giaccia AJ<\/u>, Le QT<\/u>, Shimizu S<\/u>, Shirato H<\/u>, Nam JM<\/u>. Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition. Cancers <\/em>(Basel). 2019 Aug 16;11(8). pii: E1192. doi: 10.3390\/cancers11081192. [Overseas journal] *, i), ii), \u25cb<\/li>\n
  7. Yusuke Nomura, Qiong Xu<\/u>, Hiroki Shirato<\/u>, Shinichi Shimizu<\/u>, Lei Xing<\/u>, Projection-domain scatter correction for cone beam computed tomography using a residual convolutional neural network. (Received 12 December 2018; revised 8 April 2019; accepted for publication 24 April 2019; Medical Physics<\/em>, in press, 2019 *, i), \u25cb<\/li>\n
  8. C Liu, Z Li, W Hu, L Xing<\/u>, H Peng<\/u> Range and dose verification in proton therapy using proton-induced positron emitters and recurrent nenuralnetworks (RNNs) \u2013 Physics in Medicine & Biology<\/em>, 2019 \u2013 iop.org [Overseas journal] *, i)<\/li>\n
  9. Z Li, Y Wang, Y Yu, K Fan, L Xing<\/u>, H Peng<\/u> Machine Learning Approaches for Range and Dose Verification in Proton Therapy Using Proton-induced Positron Emitters \u2013 Medical physics<\/em>, 2019 \u2013 Wiley Online Library [Overseas journal] *, i)<\/li>\n
  10. Y Yu, Z Li, D Zhang, L Xing<\/u>, H Peng<\/u>Simulation Studies of time reversal- based photoacoustic reconstruction for range and dose verification in proton therapy \u2013 Medical physics<\/em>, 2019 \u2013 Wiley Online Library [Overseas journal] *, i)<\/li>\n
  11. Demirkan, Irem, Mehmet Burcin Unlu<\/u>, and Bukem Bilen. Determining sodium diffusion through acoustic impedance measurements using 80 MHz Scanning Acoustic Microscopy: Agarose phantom verification. Ultrasonics94<\/em> (2019): 10-19. [Overseas journal] *<\/li>\n <\/ol>\n

    Other Original Papers \u2013 major paper only<\/h3>\n

    Japanese Journals (including those in English)<\/h4>\n
      \n
    1. Mizumachi T, Kano S, Homma A, Akazawa M, Hasegawa C, Shiroishi Y, Okamoto C,Kumagai S, Nishimura M, Takasaki H, Takeda H, Yasuda K<\/u>, Minatogawa H, Dekura Y,Onimaru R, Shirato H<\/u>, Fukuda S. [A Nutritional Supplement with a High Blend Ratio of \u03c9-3 Fatty Acids(Prosure\u00ae) Reduces Severe Oral Mucositis and Body Weight Loss for Head and Neck Cancer Patients Treated with Chemoradiotherapy]. Gan To Kagaku Ryoho.<\/em> 2019 Apr;46(4):685-689. Japanese. PubMed PMID: 31164507. [Japanese journal] *<\/li>\n
    2. Takayuki Hashimoto<\/u>, Shinichi Shimizu<\/u>,Seishin Takao<\/u>,Shunsuke Terasaka, Akihiro Iguchi, Hiroyuki Kobayashi, Takashi Mori,Takaaki Yoshimura, Yuto Matsuo, Masaya Tamura, Taeko Matsuura<\/u>, Yoichi M. Ito, Rikiya Onimaru and Hiroki Shirato<\/u> , Clinical experience of craniospinal intensity modulated spot-scanning proton therapy using large fields for central nervous system medulloblastomas and germ cell tumors in children, adolescents, and young adults. Journal of Radiation Research<\/em>, Vol. 60, No. 4, 2019, pp. 527\u2013537doi: 10.1093\/jrr\/ rrz022 Advance Access Publication: 21 May 2019 [Japanese journal] *, i) <\/li>\n <\/ol>\n

      Overseas Journals<\/h4>\n
        \n
      1. Miyamoto N, Maeda K, Abo D, Morita R, Takao S<\/u>, Matsuura T<\/u>, Katoh N<\/u>, Umegaki K<\/u>,Shimizu S<\/u>, Shirato H<\/u>. Quantitative evaluation of image recognition performance of fiducial markers in real-time tumor-tracking radiation therapy. Phys Med.<\/em> 2019 Sep;65:33-39. doi: 10.1016\/j.ejmp.2019.08.004. Epub 2019 Aug 12. PubMed PMID:31430584. [Overseas journal] *, i), ii)<\/li>\n
      2. Uchinami Y, Suzuki R, Katoh N<\/u>, Taguchi H, Yasuda K<\/u>, Miyamoto N<\/u>, Ito YM, Shimizu S<\/u>, Shirato H<\/u>. Impact of organ motion on volumetric and dosimetric parameters in stomach lymphomas treated with intensity-modulated radiotherapy. J Appl Clin Med Phys.<\/em> 2019 Aug;20(8):78-86. doi: 10.1002\/acm2.12681. Epub 2019 Aug 10. PubMed PMID: 31400082; PubMed Central PMCID: PMC6698764. [Overseas journal] *, i), ii)<\/li>\n
      3. Ishikawa H, Tsuji H, Murayama S, Sugimoto M, Shinohara N, Maruyama S, Murakami M, Shirato H<\/u>, Sakurai H. Particle therapy for prostate cancer: The past, present and future. Int J Urol.<\/em> 2019 Oct;26(10):971-979. doi: 10.1111\/iju.14041. Epub 2019 Jul 8. Review. PubMed PMID: 31284326. [Overseas journal] *, i)<\/li>\n
      4. Endo K, Takahata M, Sugimori H, Yamada S, Tadano S, Wang J, Todoh M, Ito YM, Takahashi D, Kudo K, Iwasaki N. Magnetic resonance imaging T1 and T2 mapping provide complementary information on the bone mineral density regarding cancellous bone strength in the femoral head of postmenopausal women with osteoarthritis.Clin Biomech<\/em> (Bristol, Avon). 2019 May;65:13-18. doi: 10.1016\/ j.clinbiomech.2019.03.010. Epub 2019 Mar 20. [Overseas journal] *<\/li>\n
      5. Morita R1 Abo D<\/u>, Sakuhara Y, Soyama T, Katoh N<\/u>, Miyamoto N<\/u>, Uchinami Y, Shimizu S<\/u>, Shirato H<\/u>, Kudo K<\/u> Percutaneous insertion of hepatic fiducial true-spherical markers for real-time adaptive radiotherapy. Minim Invasive Ther Allied Technol.<\/em> 2019 Sep 13:1-10. [Overseas journal] *, i), ii)<\/li>\n
      6. Oyama-Manabe N<\/u>, Manabe O, Naya M, Kudo K<\/u>, Tamaki N. Comprehensive evaluation of myocardial ischemia with dynamic perfusion CT. Annals of Nuclear Cardiology<\/em> 2019; 5(1) 79-83 [Overseas journal] *<\/li>\n
      7. Abe N, Kato M, Fujieda Y, Narita H, Tha KK<\/u>, Atsumi T. Tumor necrosis factor alpha blockade for non-inflammatory pain: beyond inflammation? Scand J Rheumatol<\/em>. 48(6): 519-521, 2019 May 28:1-3. [Overseas journal] *<\/li>\n
      8. Kazumata K, Tha KK<\/u>, Tokairin K, Ito M, Uchino H, Kawabori M, Sugiyama T. Brain Structure, Connectivity, and Cognitive Changes Following Revascularization Surgery in Adult Moyamoya Disease. Neurosurgery<\/em>. 2019 Jun 3. pii: nyz176. doi: 10.1093\/neuros\/nyz176. [Overseas journal] *<\/li>\n
      9. Kato K, Yasojima N, Tamura K, Ichikawa S, Sutherland K<\/u>, Kato M, Fukae J, Tanimura K, Tanaka Y, Okino T, Lu Y, Kamishima T. Detection of Fine Radiographic Progression in Finger Joint Space Narrowing Beyond Human Eyes: Phantom Experiment and Clinical Study with Rheumatoid Arthritis Patients. Sci Rep.<\/em> 2019 Jun 12;9(1):8526. doi: 10.1038\/s41598-019-44747-6. PMID: 31189913 [Overseas journal] *<\/li>\n
      10. Fujimori M, Kamishima T, Narita A, Henmi M, Kato M, Sutherland K<\/u>, Nishida M, Tanaka Y, Yutong L, Tanimura K, Atsumi T. Quantitative power Doppler signal assessment in the subchondral bone region of the metacarpophalangeal joint is an effective predictor of radiographic progression in the hand of rheumatoid arthritis: a pilot study. Rheumatol Int.<\/em> 2019 Aug;39(8):1413-1421. doi: 10.1007\/s00296-019-04320-w. Epub 2019 May 14. PMID: 31089859 [Overseas journal] *, i)<\/li>\n
      11. Fujimori M, Murakami K, Sugimori H, Lu Y, Sutherland K<\/u>, Oki N, Aoki T, Kamishima T. Intravoxel incoherent motion MRI for discrimination of synovial proliferation in the hand arthritis: A prospective proof-of-concept study. J Magn Reson Imaging<\/em>. 2019 Oct;50(4):1199-1206. doi: 10.1002\/jmri.26660. Epub 2019 Jan 31 PMID: 30706568 [Overseas journal] *, i)<\/li>\n
      12. Kenneth Sutherland<\/u> Toshiyuki Hamada2 . Masayori Ishikawa<\/u> 1A. Naoki Miyamoto<\/u> 1 \u00b75 . Masahiro Mizuta3 . Hiroyuki Date4 . Hiroki Shirato<\/u> 1 ,5 3D Transformation Matrix Calculation and Pixel Intensity Normalization for the Dual Focus Tracking System. Journal of Medical and Biological Engineering<\/em> August 2019 https:\/\/doi.org\/10.1007\/s40846 019-00474-x [Overseas journal] *, i), ii)<\/li>\n
      13. Shimizu Y, Kudo K<\/u>, Kameda H, Harada T, Fujima N, Toyonaga T, Tha KK<\/u>, Shirato H<\/u>. Prediction of Hypoxia in Brain Tumors Using a Multivariate Model Built from MR Imaging and (18)F-Fluorodeoxyglucose Accumulation Data. Magn Reson Med Sci.<\/em> 2019 Oct 15. doi: 10.2463\/mrms.mp.2019-0049. [Epub ahead of print] PubMed PMID: 31611541. [Overseas journal] *, i)<\/li>\n
      14. Furuya S, Naya M, Manabe O, Hirata K, Ohira H, Aikawa T, Koyanagawa K, Magota K, Tsujino I, Anzai T, Kuge Y, Oyama-Manabe N, Kudo K, Shiga T, Tamaki N.18F-FMISO PET\/CT detects hypoxic lesions of cardiac and extra-cardiac involvement in patients with sarcoidosis.J Nucl Cardiol<\/em> 2019 Dec 9. doi: 10.1007\/s12350-019-01976-6. [Epub ahead of print] [Overseas journal] *, ii)<\/li>\n
      15. Kobayashi K, Manabe O, Hirata K, Yamaguchi S, Kobayashi H, Terasaka S, Toyonaga T, Furuya S, Magota K, Kuge Y, Kudo K, Shiga T, Tamaki N. Influence of the scan time point when assessing hypoxia in 18F-fluoromisonidazole PET: 2 vs. 4 h.Eur J Nucl Med Mol Imaging<\/em>. 2019 Nov 28. doi: 10.1007\/s00259-019-04626-8. [Epub ahead of print] [Overseas journal] *, i)<\/li>\n
      16. Tha KK<\/u> Cognitive Impairment, Neuroinflammation, and MRI. Journal of Magnetic Resonance Imaging<\/em> manuscript number JMRI-19-1437) [accepted] [Overseas journal] *, i)<\/li>\n
      17. Ueno, Koki & Matsuura, Taeko<\/u> & Hirayama, Shusuke & Takao, Seishin<\/u> & Ueda, Hideaki & Matsuo, Yuto & Yoshimura, Takaaki & Umegaki, Kikuo<\/u>. Physical and biological impacts of collimator-scattered protons in spot-scanning proton therapy (2019). Journal of Applied Clinical Medical Physics<\/em>. 20. 10.1002\/acm2.12653. [Overseas journal] *, i), ii)<\/li>\n
      18. Naoki Miyamoto, Kouhei Yokokawa, Seishin Takao, Taeko Matsuura, Sodai Tanaka, Shinichi Shimizu, Hiroki Shirato, Kikuo Umegaki. Dynamic gating window technique for the reduction of dosimetric error in respiratory-gated spot-scanning particle therapy: an initial phantom study using patient tumor trajectory data (2020). Journal of Applied Clinical Medical Physics<\/em>. Accepted [Overseas journal] *, i)<\/li>\n
      19. Shusuke Hirayama, Taeko Matsuura, Koichi Yasuda, Seishin Takao, Takaaki Fujii, Naoki Miyamoto, Kikuo Umegaki, and Shinichi Shimizu, Difference in LET-based biological doses between IMPT optimization techniques: robust and PTV-based optimizations (2020) Journal of Applied Clinical Medical Physics<\/em>. Accepted [Overseas journal] *, i), ii)<\/li>\n
      20. Yokokawa, K, Furusaka, M, Matsuura, T, Hirayama, S, Umegaki, K, A new SOBP-formation method by superposing specially shaped Bragg curves formed by a mini-ridge filter for spot scanning in proton beam therapy, Physica medica<\/em>, November 2019; 67, 70-762019-11, ISSN: 1120-1797 [Overseas journal] *, i)<\/li>\n
      21. Hirayama S, Matsuura T, Yasuda K, Takao S, Fujii T, Miyamoto N, Umegaki K, Shimizu S, Difference in LET-based biological doses between IMPT optimization techniques: Robust and PTV-based optimizations. (2020) Journal of Applied Clinical Medical Physics<\/em>. 2020 Mar 9. doi: 10.1002\/acm2.12844 [Overseas journal] *, i), ii)<\/li>\n
      22. Hashimoto S, Furukawa S, Hashimoto A, Tsutaho A, Fukao A, Sakamura Y, Parajuli G, Onodera Y<\/u>, Otsuka Y, Handa H, Oikawa T, Hata S, Nishikawa Y, Mizukami Y, Kodama Y, Murakami M, Fujiwara T, Hirano S, Sabe H. ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer. Proc Natl Acad Sci U S A<\/em>. 2019 Aug 27;116(35):17450-17459. doi:10.1073\/pnas. 1901765116. Epub 2019 Aug 9. [Overseas journal] *<\/li>\n
      23. Mazaki Y, Takada S, Nio-Kobayashi J, Maekawa S, Higashi T, Onodera Y<\/u>, Sabe H. Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60\u202fcells. Biochem Biophys Res Commun<\/em>. 2019 Jun 4;513(3):708-713. doi:10.1016\/ j.bbrc.2019.04.037. Epub 2019 Apr 12. [Overseas journal] *, ii)<\/li>\n
      24. Mazaki Y, Higashi T, Onodera Y<\/u>, Nam JM<\/u>, Hashimoto A, Hashimoto S, Horinouchi T, Miwa S. Endothelin type B receptor interacts with the 78-kDa glucose-regulated protein. FEBS Letters<\/em>, Mar;593(6):644-651, 2019 [Overseas journal] *, i), ii)<\/li>\n
      25. Annan DA, Maishi N, Soga T, Dawood R, Li C, Kikuchi H, Hojo T, Morimoto M, Kitamura T, Alam MT, Minowa K, Shinohara N, Nam JM<\/u>, Hida Y, Hida K. Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment. Cell Commun Signal<\/em>., Dec 17; 17(1):169, 2019 [Overseas journal] *, ii)<\/li>\n
      26. Wu PH<\/u>, Opadele AE, Onodera Y<\/u>, Nam JM<\/u> Targeting Integrins in Cancer Nanomedicine: Applications in Cancer. Cancers<\/em>, 11(11), 1783, 2019 [Overseas journal] *, i)<\/li>\n
      27. Fujima N, Shimizu Y, Yoshida D, Kano S, Mizumachi T, Homma A, Yasuda K<\/u>, Onimaru R, Sakai O, Kudo K<\/u>, Shirato H<\/u>. Machine-Learning-Based Prediction of Treatment Outcomes Using MR Imaging-Derived Quantitative Tumor Information in Patients with Sinonasal Squamous Cell Carcinomas: A Preliminary Study. Cancers (Basel). 2019 Jun 10<\/em>;11(6). pii: E800. doi: 10.3390\/ cancers11060800. PubMed PMID: 31185611; PubMed Central PMCID: PMC6627127. [Overseas journal] *, i)<\/li>\n
      28. Hayashi T, Nakamura T, Kimura Y, Yoshida M, Someya M, Kawakami H, Sakuhara Y, Katoh N<\/u>, Takahashi K, Ambo Y, Miura K, Motoya M, Tanaka E, Murakawa K, Yamabuki T, Yamazaki H, Katanuma A, Hirano S; Hokkaido Pancreatic Study Group. Phase 2 Study of Neoadjuvant Treatment of Sequential S-1-Based Concurrent Chemoradiation Therapy Followed by Systemic Chemotherapy with Gemcitabine for Borderline Resectable Pancreatic Adenocarcinoma (HOPS-BR 01). Int J Radiat Oncol Biol Phys<\/em>. 2019;105:606-617. [Overseas journal] *<\/li>\n
      29. Kushiya H, Noji T, Abo D<\/u>, Soyama T, Tanaka K, Nakanishi Y, Asano T, Nakamura T, Tsuchikawa T, Okamura K, Hirano S. Treatment of bleeding from a portion of pancreatojejunostomy after pancreaticoduodenectomy with division of the splenic vein: two case reports. Surg Case Rep.<\/em> 2019 Aug 8;5(1):128. doi: 10.1186\/s40792-019-0687-5. [Overseas journal] *<\/li>\n
      30. Shimada S, Kamiyama T, Yokoo H, Orimo T, Wakayama K, Nagatsu A, Kakisaka T, Kamachi H, Abo D<\/u>, Sakuhara Y, Taketomi A. Hepatic hypertrophy and hemodynamics of portal venous flow after percutaneous transhepatic portal embolization. BMC Surg<\/em>. 2019 Feb 18;19(1):23. doi: 10.1186\/s12893-019-0486-8. [Overseas journal] *, ii)<\/li>\n
      31. Sakuhara Y, Nishio S, Hattanda F, Soyama T, Takahashi B, Abo D,<\/u> Mimura H. Initial experience with the use of tris-acryl gelatin microspheres for transcatheter arterial embolization for enlarged polycystic liver. Clin Exp Nephrol<\/em>. 2019 Jun;23(6):825-833. doi: 10.1007\/s10157-019-01714-9. Epub 2019 Feb 15 [Overseas journal] *<\/li>\n <\/ol>\n
        \n
          \n
        • Papers where “GI-CoRE” is stated as an affiliated institution of a Japanese or overseas researcher, or those mentioning “Hokkaido University ” in the acknowledgements, are marked with a “* (asterisk)” and the applicable author name is underlined.<\/li>\n
        • Among the papers with “* (asterisk)”, papers where “GI-CoRE” is stated as an affiliated institution are marked with “i)”, and papers which mention “Hokkaido University” in the acknowledgements are marked with “ii)”.<\/li>\n
        • Papers where GI-CoRE researchers of Hokkaido University and Stanford University are stated are marked with”\u25cb”<\/li>\n <\/ul>\n <\/section>","protected":false},"excerpt":{"rendered":"International Collaborative Papers Jihun Kwon, Rajalekha M. Rajamahendiran, Needa A. Virani, Sijumon Kunjachan […]","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page.php","meta":[],"_links":{"self":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/pages\/83"}],"collection":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/comments?post=83"}],"version-history":[{"count":0,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/pages\/83\/revisions"}],"wp:attachment":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/gcb.med\/JP\/wp-json\/wp\/v2\/media?parent=83"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}